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:: Volume 18, Issue 1 (3-2016) ::
J Gorgan Univ Med Sci 2016, 18(1): 53-57 Back to browse issues page
Abortificient effect of mulberry white root in mice
Motaghi B * 1, Rafieian M2 , Asgari A3
1- Midwifer, Faculty of Nursing and Midwifery, Shahrekord University of Medical Sciences, Shahrekord, Iran , b.motaghi14@gmail.com
2- Professor, Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
3- Ph.D in Physiology, Tarbiat Modares University, Tehran, Iran
Abstract:   (13144 Views)

Background and Objective: Due to an increase in spontaneous abortions finding a safe and secure method is inevitable. Some medicinal herbs have abortifacient properties. This study was done to determine the effect of abortifacient effect of mulberry white root in mice. Methods: In this experimental study, 50 mice dams were randomly allocated into five groups including control, sham and experimental group 1, 2 and 3. Animals in control group did not receive any substance. Animals in sham group were received normal saline, intraperitoneally. Animals in experimental group 1, 2 and 3 were received doses of 50, 70 and 90 mg/kg/bw of the alcoholic extract of root of mulberry white during the 7th to 12th days of pregnancies, intraperitoneally, respectively. At the 16th day of the pregnancy the uterine tubes of mice were removed and the absorbed fetuses were recorded. Results: The mean of absorb fetuses was 7.4, 7.6, 1.8 and 3.1 in the experimental group 1, 2, 3 and sham, respectively. There was a significant relation between the mean number of aborted fetuses and concentration of strawberry root (P<0.05). The apparent anomaly in fetus was not recorded. Conclusion: Root of mulberry white has abortifacient effect with dose-dependent manner.

Keywords: White mulberry, Fetus absorption, Mouse
Full-Text [PDF 155 kb] [English Abstract]   (19803 Downloads) |   |   Abstract (HTML)  (421 Views)  
Type of Study: Original Articles | Subject: Physiology - Pharmacology
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Motaghi B, Rafieian M, Asgari A. Abortificient effect of mulberry white root in mice. J Gorgan Univ Med Sci 2016; 18 (1) :53-57
URL: http://goums.ac.ir/journal/article-1-2656-en.html


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Volume 18, Issue 1 (3-2016) Back to browse issues page
مجله دانشگاه علوم پزشکی گرگان Journal of Gorgan University of Medical Sciences
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