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Background & Objective: Asymptomatic bacteriuria (ASB) is a significant problem during pregnancy because it can be developed into more severe infections that may have repercussions for the health of the mother and unborn child. The aim of this study was to assess relationship between asymptomatic bacteriuria and preeclampsia in Gorgan. Materials & Methods: This case control study performed on 150 preeclamptic women (Case group) compared with 150 healthy pregnant women (Control group) who hospitalized from 2002 to 2002 (Gravid, age and history of preeclampsia was matched with 2 group). The questionnaires and checklist was completed, urine analysis, and urine culture were performed. The data analyzed with SPSS software and statistical descriptive and analytic such as: T-student, U-Mann Whitney. Results: The risk of preeclampsia in pregnant women with ABS was 3.2 fold to healthy pregnant women (OR=3.22, CI 95% for OR=1.99, 5.21). Conclusion: Asymptomatic bacteriuria may predisposing factor to preeclampsia, we suggest screening of ASB in the 1st prenatal care and follow in 2nd and 3rd trimester of pregnancy o prevent the main side effect in pregnancy and the safety of mothers.

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Background & Objective: Preeclampsia is a common complications of pregnancy it’s about 5-7% in pregnants and it may complicate mother or fetus which ends with death. The purpose of this study was to determine the value of the protein/creatinine ratio in prediction of 24-hour urine total among women with suspected preeclampsia. Materials & Methods: 60 women who were evaluated for suspected preeclampsia at ?24 weeks of gestation were studied prospectively in Deziani Hospital Gorgan. There was no concurrent or preexisting systemic disease. They were undergoing a 24-hour urine collection for the determination of proteinuria. A single voided urine specimen was obtained after completion of the 24-hour urine collection and analyzed for the P/C ratio. Results: The random urinary protein to creatinine ratios is strongly associated with the 24-hour total protein excretion (P<0.05, R=0.75). The best cut off of 0.5 yields a sensitivity of 47% and a specificity of 100%. Conclusion: The random urinary protein to creatinine ratio could replace the 24-hour urine collection as a simple, faster more useful method for the diagnosis of significant proteinuria.

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Background & Objective: Despite advances in medical sciences, preeclampsia and eclampsia are still among chief causes of maternal mortality worldwide. In this study, we used classification and regression trees to investigate the role of certain inherent and maternity care factors in severe preeclampsia. Materials & Methods: This study was done on 1643 pregnant women admitted at 4 hospitals in Iran with one of the 53 maternity complaints were enrolled in this study during 2005. Variables of socioeconomic status, history of pregnancy and diseases, health care visits numbers awareness of warning signs, and the body mass index before pregnancy were recorded in the analysis model as predictors, and preeclampsia severity was entered as the dependent variable. A non-parametric method, known as the classification and regression tree was used to predict the studied consequence. Model validation was done using subsets of the study sample. The results were compared with logistic regression analysis. Results: The incidence of preeclampsia among the studied patients was 5.2%. In model 1, variables of frequent headaches and epigastric pain during pregnancy, the number of previous pregnancies, and the amount of maternal care received were predictive of severe preeclampsia. In model 2, only frequent headaches and the number of previous pregnancies were found predictive. Sensitivity for model 1 and 2 was 47.8% and 39.1%, respectively, and specificity was 96.8% and 93.6%, respectively. In logistic regression analysis, only frequent headache was related to severe preeclampsia (OR=2.5, CI 95%: 1.3-5.0). Conclusion: This study showed that using of variables that can be measured during maternity care visits to predict severe preeclampsia. Regarding the simple interpretation of tree models and their application in clinical decision making, which can be used in different levels of the health care system.

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Background&Objective: Preeclampsia is a common complication of pregnancy it’s a bout 5-7 percent in pregnants and it may complicate mother or fetus which ends with death. The purpose of this study was to determine the value of the protein / creatinine ratio in prediction of 24-hour urine total among women with suspected preeclampsia. Materials&Methods: 150 women who were evaluated for suspected preeclampsia at ?20 weeks of gestation were studied prospectively in Az-zahra and Emam hospital Sari. There was no concurrent or preexisting systemic disease. They were undergoing a 24-hour urine collection for the determination of proteinuria. A single voided urine specimen was obtained after completion of the 24-hour urine collection and analyzed for the P/C ratio. Results: The randome urinary protein to creatinine ratios is strongly associated with the 24-hour total protein excretion (P<0.05, r = 0.37). The best cut off of 0.175 yieldes a sensitivity of 85.9% and a specificity of 66%. Conclusion: The random urinary protein to creatinine ratio could replace the 24-hour urine collection as a simple, faster more useful method for the diagnosis of significant protenuria.

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Pulmonary aspiration of gastric contents during the peri-operative period is rare but with significant morbidity and mortality. A 21 years old pregnant woman with preeclampsia was scheduled for an emergency cesarean section under spinal anesthesia. After 18 hours of operation, epilepticus status was occurred. One day after control of seizure, aspiration pneumonitis was diagnosed and treated with mechanical ventilation and positive end-expiratory pressure (PEEP). In patients with the history of loss, consciousness, complication of aspiration, aspiration pneumonia and pneumonitis particularly should be considerated. In case of onset of pneumonitis, PEEP treated procedure with other mechanical ventilation is recommaded.

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Background and Objective: Androgens are among the causative factors in preeclampsia. This study was done to compare the serum androgens and progesterone in preeclampsia and normal pregnancy. Materials and Methods: This case-control study was done on 30 preeclamptic and 30 healthy pregnant women in Gorgan, Iran. Higher or equal to 140/90 mmHg and proteinuria equal or more than +1 in dip stick test in the third trimester of pregnancy were considered as the diagnostic criteria of preeclampsia. Progesterone, free and total testosterone, and dehydroepiandrosterone sulphate (DHEA) were measured by ELISA method. Results: Total testosterone level was 1.8±0.3 ng/ml and 1.3±0.9 ng/ml in cases and controls, respectively. This difference was not significant. Progesterone was lower in cases (95±46.9 ng/ml) than in controls (165.4±75 ng/ml) (P<0.01). Free testosterone and DHEA were 5.6±2.3 ng/ml and 1±0.5 ng/ml in cases, respectively which was significantly higher than the controls (3.2±1.5 ng/ml and 0.7±0.4 ng/ml, respectively) (P<0.045). Conclusion: Serum level of free testosterone, DHEA and progesterone increased and reduced respectivley in preeclampsia.

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Background and Objective: Thrombophilia is characterized by increasing blood coagulability. It causes preeclampsia and repeated abortions. This study was done to determine the corrolation of coagulation factors deficiency with preeclampsia. Method: This case-control study was carried out on 142 pregnant women with preeclampsia as caess and 142 pregnant women without preeclampsia as controls. Coagulation factors including Prs, prc, and anti-thrombin-3 were measured using ELISA and chromogenic methods. Results: Prs deficiency was found in 2 (1.4%) and 6 (4.2%) of cases and controls, respectively. This difference was not significant. Prc and anti-thrombin- 3 deficiencies was not found in cases and controls. Conclusion: There is not any relation between deficiencies of coagulation factors with preeclampsia.

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Background and Objective: Liver enzyme tests are usually normal or slightly increased during pregnancy. Abnormal liver enzyme tests are seen in 3% of pregnancies and should be evaluated immediately. Early detection and timely treatment is the key to successful treatment. This study was carried out to determine the prevalence of abnormal liver enzymes and pregnancy outcome in women admitted to Sayyad-e-Shirazi hospital in Gorgan-north of Iran.
Methods: This descriptive, cross-sectional study was carried out on 73 hospitalized pregnant women out of 6680 pregnant women in the Sayyad Shirazi hospital, in north of Iran during April to September 2015. Clinical information was including laboratory tests, final diagnosis and complications postpartum of 73 women with impaired liver enzymes.
Results: The most common cause of abnormal liver enzymes were pre-eclampsia in pregnant women (16 patients 21.9%) which occured in the third trimester. HELLP syndrome was observed in 9 (12.3%) of patients which occurred in the third trimester. Also in 3 cases (4.1%) eclampsia was reported in the third trimester.
Conclusion: Due to the high incidence of pre-eclampsia and HELLP syndrome in women with impaired liver enzymes, careful examination of patients, especially in the third trimester of pregnancy is essential.