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Background and Objective: Nowaday many diabetic patients interested in using medicinal herbs to relieve the symptoms of their disease in spite of the availability of synthetic drugs, one of such herbal medicine is green tea, studies about effects of this plant on blood glucose, weight of diabetes is contradict and suitable dosage is not mentioned, thus this study was done to determine the effect of green tea extract on blood glucose and body weight in male induced diabetic Rats. Materials and Methods: In this experimental study 40 wistar male Rats with body weight of 230±20 purchased and kept standard situation subsequently 8 of them considered as normal group and the reminder became diabetic by 50mg/kg IP by streptozotosin. After 2 weeks animals with blood glucose of 200-500 mg/dl were considered as diabetic and divided in 4 groups with 8 animals in each. Then 3 groups of them daily was feed with 50, 100 and 200 mg/kg of extract by feeding tube for 6 weeks, diabetic control group and non-diabetic group also was feed with DMSO10% as well. BS and body weight were assessed at 2nd, 4th, 6th week after daily feeding by different doses of green tea extract, and at last results were analyzed by using student t-test and one way ANOVA. Results: The mean of blood glucose of diabetic control group were significantly higher than non-diabetic group and blood glucose of diabetic groups that was feed with 50, 100 and 200mg/kg of extract was significantly lower than diabetic control group. Body weight of 3 treatment groups were not significantly reduced. Conclusion: This study showed that green tea extract has an antidiabetic effect and suitable dosage of this extract was 100mg/kg.

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Background and Objective: Failure of tuberculosis (TB) treatment is a major problem of health systems in developing countries. This study was done to identify the Risk factors of tuberculosis treatment failure in the Sistan and Bulochestan province, the high risk region in South-East of Iran. Methods: This case – control study was carried out on 52 tuberculosis patients (smear -positive and category- I therapy) treated during six months period. Patients with treatment failure were considered as cases and patients with negative smear after 6 months of treatment with anti-tuberculosis (TB) medicines were considered as control group. Demographic, clinical and treatment outcomes were recorded for each patient. The multivariate logistic regression was performed to determine the predictors of treatment failure. Results: Family history of tuberculosis (95% CI: 1-12.56, OR=3.55, P=0.04,), smoking (95% CI:1.58-51.21, OR=9, P=0.01), drug addiction before or during the treatment period (95% CI: 5.28-123.91, OR=25.6, P=0.0001) and low body weight (95% CI:1.05-12.6, OR=3.65, P=0.04) were risk factors for treatment failure. Conclusion: Family history of tuberculosis, weight loss during treatment, smoking and drug addiction, were considered as risk factors for treatment failure in National Tuberculosis Control Programme (NTCP) in south-east of Iran.

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Background and Objective: Bariatric surgery is the most effective treatment for morbid obesity. The classic procedure, jejunoileal bypass, has many complications. This study was carried out to assess the evaluation of clinical complications in morbid obese patients after modified jejunoileal bypass surgery. Method: This descriptive – analytic study was carried out on 120 morbid obese patients referred for bariatric surgery. A modified jejunoileal bypass was performed in which the defunctionalized organ eliminated by anastomosing its ends to the gall bladder and cecum. Weight loss and clinical complications were recorded after one year follow up. Results: The mean weight and body mass index reduced from 136 kg and 48 kg/m2 before surgery to 83 kg and 29/8 kg/m2 after one year follow up, respectively (P<0.05). Before surgery, articular pain (24.3%), dispana (21.6%), cardiovascular disorders (10.8%), fatty liver (5.4%) and sleep disorder (5.4%) due to obesity were recorded. One year follow up after surgery, articular pain (1.5%) and dispana (1.5%) were seen in patiants. No serious post-operative clinical complication was observed. Conclusion: One year follow up after surgery showed that the modified jejunoileal bypass is very effective in reducing body weight and does not lead to serious complication.

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Background and Objective: Modification of life style, nutrional regiment and insulin therapy is used for improvement of pregnancy outcomes in pregnant women with gestational diabetes mellitus (GDM). This study was done to evaluate the effect of the dietary approaches to stop hypertension (DASH) eating plan on pregnancy outcomes in pregnant women with gestational diabetes mellitus. Methods: In this clinical trial study, 52 women with GDM were randomly divided into DASH and control groups for 4 weeks. The control diet contained 45-55% carbohydrates, 15-20% protein and 25-30% total fat. The DASH was rich in fruits, vegetables, whole grains and low-fat dairy products, and contained lower amounts of saturated fats, cholesterol and refined grains with a total of 2400 mg/day sodium. The numbers of women whom commenced insulin therapy after dietary intervention, the mode of delivery and prevalence of polyhydramnios were assessed. The length, weight and head circumference of infants were measured during the first 24 h after birth. Results: 46.2% of women in the DASH group needed to have a cesarean section, this rate for the control group was 80.8% (P<0.05). The percentage of those who needed to commence insulin therapy after intervention was 23% for DASH group vs 73% for controls (P<0.05). Infants born to mothers on the DASH group had significantly lower body weight (3222.7 vs 3818.8 g, P<0.05), head circumference (34.2 vs 35.1 cm, P<0.05) and ponderal index (2.50 vs 2.87 kg/m3, P<0.05) compared to those born to mothers on the control diet. Conclusion: Consumption of dietary approaches to stop hypertension for 4 weeks among pregnant women with GDM resulted in improved pregnancy outcomes.

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Background and Objective: Obesity presented as the most pivotal public health problem. Motivational interviewing is a client-centered and direct technique to improve intrinsic motivation of people to change behavior using search and resolve ambivalence that its beneficial outcomes have widely been confirmed. This study was carried out to evaluate the effect of motivational interviewing on weight loss in women. Methods: In this randomized clinical trial study, 150 women with overweight and obesity were randomly divided into control, motivational interviewing and motivational interviewing and intention implementation groups. Data were collected through a researcher made questionnaire at baseline and 2 month follow up. Results: The score of protection motivation theory constructs including susceptibility, severity, rewards, self-efficacy, response efficacy and cost were significantly increased in the two intervention groups compared to the control group (P<0.05). Anthropometric characteristics were significantly reduced in the motivational interviewing and motivational interviewing with intention implementation group (P<0.05) in compare to the control group (P<0.05). Conclusion: Motivational interviewing integrated into intention implementation causes weight loss and increase the constructs score in women.