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Showing 23 results for Besharat
Ali Jafari , Zahra Norouzi , Fazel Isapanah Amlashi , Iman Shahabi Nasab , Puria Qadirian , Shahin Shah Yousefi , Mohammad Taqi Badeleh Shamushaki , Seyyedeh Fatemeh Mousavi Emadi , Sima Besharat ,
Volume 24, Issue 4 (12-2022)
Abstract
Background and Objective: Celiac disease is a malabsorption disorder that could result in various psychological consequences if patients do not adhere to a gluten-free diet. This study aimed to determine the frequency of major depressive disorder and its relationship with adherence to a gluten-free diet among patients with celiac disease.
Methods: This descriptive-analytical study was conducted on 47 patients with celiac disease (30 women and 17 men) with an average age of 40.88 ± 10.7 years who had been referred to the Golestan Research Center of Gastroenterology and Hepatology during the summer of 2019. Patients were invited to complete a 13-item Beck Inventory. Celiac Dietary Adherence Test (CDAT) was used to assess adherence from the patients' point of view, and Standardized Dietician Evaluation (SDE) was used to evaluate adherence to the diet from the interviewer's perspective.
Results: Overall, 28 people (59.6%) with celiac disease reported some degree of depression. Based on the SDE, the adherence rate of patients to a gluten-free diet was 83%. The association between adherence to a gluten-free diet and the prevalence of depression was not significant. There was also no significant association between the prevalence of depression and the gender and age of patients.
Conclusion: Based on the results, a high percentage of patients with celiac disease have symptoms of depression. However, there is no significant relationship between adherence to a gluten-free diet and the prevalence of depression.
Maryam Esmailpour , Sima Besharat , Taghi Amiriani ,
Volume 25, Issue 2 (7-2023)
Abstract
Background and Objective: The diagnosis of inflammatory bowel disease (IBD) is performed by colonoscopy, sampling, and histopathology. Stool calprotectin is a test showing the presence of inflammation in the gastrointestinal tract. This study was done to determine the relationship between the calprotectin level in the feces and endoscopic findings in ulcerative colitis patients referred to the gastroenterology clinic in Gorgan, Iran.
Methods: This descriptive-analytical study was performed on 100 patients with ulcerative colitis referred to the gastroenterology clinic of Sayad Shirazi Hospital, Gorgan, north of Iran during 2020. The patients were asked to collect their stool samples one day before the procedure (just after taking the drug for bowel cleansing). Bowel cleansing was done by administering polyethylene glycol solution dissolved in water. The activity of ulcerative colitis was measured using the disease activity score. According to this criterion, a score greater than or equal to 5 is considered an active disease. Patients were classified into two groups: extensive or pan-colitis and left-sided colitis. Stool samples were evaluated for calprotectin in a single laboratory using a commercially available kit (Calprest- EuorociationspA. Trieste) at normal values of less than 50mg/g. The relationship between stool calprotectin with colonoscopic findings was evaluated.
Results: The average duration of infection was 4±3.1 years in the time range of 1-14 years. The calprotectin level was less than 50 μg/g in 16 patients. Stool calprotectin less than 50 µg/g was seen in only 16 patients. There was no significant relationship between the level of calprotectin and the either age or gender of patients. Most patients (84%) had active disease based on colonoscopic findings. Left-sided involvement was seen in 60% of patients. Fecal calprotectin level was significantly higher in those with acute phase and those with severe disease (P<0.05). Additionally, the calprotectin level had no significant relationship with the location of bowel involvement, extension, and disease duration.
Conclusion: This study showed that the fecal calprotectin level in patients with ulcerative colitis had a significant relationship with the severity and activity of the disease in north of Iran.
Mohsen Yekrang , Mahsa Besharat , Sima Besharat , Javad Enayat, Khadije Amjadi ,
Volume 26, Issue 4 (Winter 2024)
Abstract
Background and Objective: Poisoning is one of the most common reasons for emergency department visits worldwide. Awareness of poisoning patterns helps identify risk factors and enables early diagnosis. In Iran, narcotics are among the main causes of poisoning in children. The current study aimed to determine the prevalence of narcotics-induced poisoning in children under 18 years old referring to the Al-e-Jalil Educational and Therapeutic Center in Aq Qala, Golestan Province.
Methods: This retrospective descriptive study was conducted on 36 children aged 1 month to 18 years (22 boys and 14 girls; mean age: 51.62±36.25 months) referring to the Al-e-Jalil Educational and Therapeutic Center in Aq Qala due to narcotics-induced poisoning from 2020 to 2022. Samples were included in the study using census. Patients’ medical records were reviewed and recorded in a checklist.
Results: The highest poisoning rate stemmed from the consumption of opium (69.4%), followed by methadone (25%). Decreased level of consciousness upon hospital admission was determined to be 66.7%. The interval between poisoning and hospital admission was 5.60±3.86 hours. The mean length of hospital stay was 1.25±0.80 days, and no patients died. Most children were male (61.1%), Turkmen (69.4%), and rural residents (86.1%). The highest cases of poisoning occurred in the summer (36.1%). The most common route of contact was oral (97.2%).
Conclusion: The poisoning rate with opium is higher compared to other narcotics. However, there is strong evidence of increased opium use among young people and some evidence of increased methadone use.
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