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Rubella can be a disastrous disease in early gestation, leading to fetal death, premature delivery, and an array of congenital defects. In this study we tried to determine the preset states of immunity against Rubella virus among high-school girl pupils in Gorgan city in the north east of Iran. A total of 484 blood samples collected randomly from 484 school girl pupils for the detection of antibody against Rubella virus. Rubella antibody determined by hemagglutination inhibition (HAI) test. From total of 484 high-school girl pupils 88 (18.2%) were found susceptible to Rubella infection and 396 (81.8%) were immune to this infection. Our results show significant relation between immunity, age and history of previous vaccination against Rubella.