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Effect of four weeks of endurance training on serum level of paraoxonase-1 and lipid profile in non-athlete obese men
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Amouzad Mahdirejei T *   1, Berarei AR2 , Farzanegei P3 , Ahmadi M4 |
1- M.Sc in Exercise Physiology, Islamic Azad University, Sari Branch, Sari, Iran , taleb.amoozad@gmail.com
2- Assistant Professor, Department of Sport Physiology, Islamic Azad University, Amol Branch, Amol, Iran
3- Assistant Professor, Department of Sport Physiology, Islamic Azad University, Sari Branch, Sari, Iran
4- Ph.D in Laboratory Sciences |
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Abstract: (15504 Views) |
| Background and Objective: Paraoxonase-1 is an important factor in preventing lipid oxidation and formation of oxidized low-density lipoprotein. There are conflicting reports on the impact of physical activity on serum level of Paraoxonase-1. This study was done to determine the effect of four weeks of endurance training on serum level of Paraoxonase-1 and lipid profile in non-athlete obese men. Method: In this clinical trial study, sixteen obese healthy non-athletic men randomly divided into intervention and control groups. Subjects in interventional group were practiced endurance running periodic for four weeks, three sessions a week with 65-80% of maximum heart rate. Blood samples collected 48 hours perior the first and 48 hours following the final training. Serum level of Paraoxonase-1 and lipid profile including cholesterol, triglycerides, low-density lipoprotein and high-density lipoprotein were measured by ELISA method. Results: At the end of the training, the serum level of of paraoxonase -1 increased 15.57% (P<0.05) in interventional group and non-significantly reduced in control group (19.25%). The serum level of serum Paraoxonase-1 in interventional group significantly increased compared to controls (P<0.05). The serum level of low-density lipoprotein in interventional group significantly reduced in comparision with controls (P<0.05). Conclusion: 4 weeks of endurance training increased serum level of paraoxonase -1 and decreased low-density lipoprotein in non-athlete obese men. |
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| Keywords: Obesity, Endurance training, Paraoxonase-1 enzyme, Low-density lipoprotein, High-density lipoprotein, Male |
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Full-Text [PDF 299 kb]
[English Abstract]
(20339 Downloads)
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Type of Study: Original Articles |
Subject:
Exercise Physiology
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